Utopix Magazine- Issue 1

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Effects of Genetics and Heritability on BPD

and MDD

The Biosocial Model theorises that a

combination of biological abnormalities in

the

regulation

of

emotions

and

an

environment that lacks validation results in

emotional dysregulations (What Is the

Biosocial Theory? | CONCEPT Professional

Training, n.d.). In 2019, Skoglund et al.

carried out a family and twin study focusing

on environmental and heritability factors that

contribute to the development of BPD. They

examined the familial aggregation and

genetic propensity for BPD in Swedish

national registries, encompassing 1.8 million

individuals born between 1973 and 1993.

The data included 11,665 individuals who

received a BPD diagnosis. When compared

to individuals with unaffected relatives, the

study revealed that 46% of all BPD diagnoses

found their roots in heritability

While BPD can be triggered by childhood

trauma or neglect (Omar, 2023), wherein

the development of this illness has a

specific ‘time slot’ in which it is most likely

to be ‘triggered/unlocked’ (Bandelow et al.,

2005), depression can occur at any age. 5%

of the global adult population suffers from

depression, being most common among

young adults. Clinical depression (or MDD),

can be caused by stressful life events

including, but not limited to, pregnancy,

strained

familial

relations.

MDD

is

categorised as a mood disorder, with

feelings of sadness and anhedonia being the

defining characteristics (NHS Website,

2023).

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